Best Spa Hotels in Clayton (Missouri)

The Ritz-Carlton, St. Louis

Clayton - Missouri

The Ritz-Carlton, St Louis is a luxurious destination for those seeking an unforgettable experience. Located within a 15-minute drive of downtown Saint Louis and 10 miles from the Gateway Arch, this beautiful hotel offers a range of amenities, from in room dining to a heated outdoor pool. The staff are exceptionally friendly and attentive, making sure your stay is as comfortable as possible. The rooms are simple yet comfortable, with a great size in the suites. Housekeeping and breakfast room service are exemplary. The food in the restaurant is delicious and served by the nicest lady, Pat. With a great location and everything from the beds to staff exceeding expectations, this is heaven on earth. Whether you're looking for a romantic getaway or a family getaway, the Ritz-Carlton, St Louis is the perfect destination.

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La Quinta Inn & Suites by Wyndham St Louis Route 66

Saint Louis - Missouri

8 miles from Clayton

La Quinta Inn & Suites Route 66 is situated in a great location, just one mile away from the Laumeier Sculpture Park and Museum. The hotel offers an indoor pool, hot tub and comfortable rooms with free Wi-Fi and cable TV with HBO. Unfortunately, one customer had a less than satisfactory experience. However, the staff member on duty that night was extremely helpful and accommodating, going out of her way to make sure the customer was comfortable and their concerns were addressed. If you're looking for a quality hotel in a great location, La Quinta Inn & Suites Route 66 is worth considering, with the added bonus of a helpful and friendly staff.

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Hotel Saint Louis, Autograph Collection

Saint Louis - Missouri

8 miles from Clayton

Experience the ultimate in luxury at Hotel Saint Louis, Autograph Collection. From the moment you arrive, you'll be in awe of the beautiful decor, comfortable amenities, and friendly staff. Enjoy a seasonal outdoor swimming pool, fitness centre, free bikes, and private parking. Our rooms feature record players and albums for your entertainment, and the location is unbeatable - just 3 blocks from Busch Stadium. Get a good night's rest in our comfortable beds and wake up refreshed. Enjoy an array of amenities and on-site dining, or take advantage of our pet-friendly policies. Our staff will ensure your stay is memorable, no matter how long you stay. Come and experience the ultimate in comfort and luxury at Hotel Saint Louis, Autograph Collection.

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Four Seasons St. Louis

Saint Louis - Missouri

8 miles from Clayton

Four Seasons is the ideal choice for the discerning traveler. Our luxury hotel offers city or Gateway Arch views from all our spacious rooms, as well as an on-site restaurant and full service spa. Our friendly and helpful staff are dedicated to making your stay as comfortable and memorable as possible, offering top-notch service whether you're renting a cabana at our pool-side roof-top or enjoying a romantic dinner. We take your safety seriously, with COVID precautions in place and instant messaging for your convenience. Our amazing valet staff, comfortable beds and exceptional amenities guarantee you a stay you won't forget. Make your stay in St. Louis an unforgettable one at Four Seasons.

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Comfort Inn Sullivan

Sullivan - Missouri

54 miles from Clayton

This Sullivan Comfort Inn is conveniently located off Highway 44 and offers an indoor pool, free WiFi, cable TV with HBO and a hot tub. The front desk clerk is friendly and helpful, and you can even get a room right by the laundry room. Breakfast is good with waffles, eggs, sausage, etc. and the room is clean and spacious with a refrigerator, microwave and AC. The pool water is a little cold but the hot tub is great. The hotel staff is knowledgeable and polite and the breakfast room is kept clean and neat by a hardworking and friendly employee. Unfortunately, the orange juice is watery, so you may want to avoid that. Overall, it's a great place to stay and rest for your next destination!

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Hermann Hill

Hermann - Missouri

61 miles from Clayton

Hermann Hill is a beautiful bed and breakfast located in the heart of Missouri’s wine country, just 2 km from Hermann Historical Downtown. Our romantic cottages offer stunning views of the river, heated floors, ambient fireplaces, and jacuzzi tubs. Our on-site spa offers a relaxing massage from a trained therapist. We also offer an array of snacks, refreshments, and a Margarita machine. Breakfast is served daily and our staff is committed to providing guests with exceptional service. Whether you are seeking a romantic getaway or a family vacation, Hermann Hill is sure to exceed your expectations.

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Comfort Inn & Suites - Hannibal

Hannibal - Missouri

92 miles from Clayton

This newly renovated hotel in Hannibal, Missouri is the perfect place to stay while exploring the area. Guests can relax in the indoor pool and whirlpool after a long day of sightseeing. The hotel is clean and comfortable, and the staff is responsive to requests. However, some guests have reported issues with hot water, dirty rooms, and poor customer service. Although there have been some issues, the majority of guests have had a pleasant stay and would recommend it to others. With its modern amenities and comfortable rooms, this hotel is sure to please travelers looking for a convenient and enjoyable stay in Hannibal!

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Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

Cape Girardeau - Missouri

102 miles from Clayton

This hotel offers a perfect stay for business or pleasure. With spacious accommodations, free Wi-Fi, kitchenware, a sofa bed, an indoor pool and modern fitness center, you will have everything you need for a comfortable and enjoyable stay. Located just 3 miles from Southeast Missouri State University, you'll be close to all the attractions. Our friendly and helpful staff will make you feel right at home, and our nightly cookies and complimentary breakfast will be the perfect start to your day. For added convenience, the hotel is happy to work with you on daily reservations to accommodate any special needs. Come and relax at this hotel - you won't be disappointed!

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Holiday Inn Express and Suites Columbia University Area, an IHG Hotel

Columbia - Missouri

108 miles from Clayton

This hotel is the perfect choice for a stay in Columbia, offering free WiFi and just 4 km from the University of Missouri campus centre. Take a dip in the heated indoor pool and large hot tub, or relax in the comfortable rooms. Enjoy a delicious full breakfast, and helpful staff that go above and beyond to make sure you have what you need. With clean, spacious accommodations and great amenities, you'll have the perfect stay! Kids will love the pool, and the location is perfect for those visiting the hospital. Enjoy a delicious breakfast with plenty of options, including bacon, and a helpful staff. When you're in town, stay at this hotel.

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Holiday Inn - Executive Center-Columbia Mall, an IHG Hotel

Columbia - Missouri

112 miles from Clayton

This Columbia hotel is a great choice for any traveler! Recently updated, the hotel features a beautiful facility with comfy, spacious rooms, and friendly staff. Enjoy a workout in the 3,000 square-foot fitness center, two on-site restaurants, and a convenient location just off I-70 and close to the University of Missouri. Enjoy a complimentary breakfast, as well as a comfortable bed, clean bathrooms, and great water pressure in the shower. With an energetic staff and plenty of amenities, this hotel is sure to make your stay enjoyable.

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